Immunodeficiency disorders can lead to the development of autoimmunity

In this article, I briefly describe immunodeficiency disorders that disturb immune regulation, which can lead to the development of autoimmunity. Deficiencies in T-cell tolerance lead to autoimmunity The adaptive immune system recognizes and eliminates foreign antigens. It also has to recognize self-MHC proteins and suppress reactions to self-antigens in the host. The induction of tolerance … Read more >>