The role of invariant chain in MHC class II trafficking and immune defense

In this article, I briefly describe the role of the invariant chain in guiding the transport of class-II MHC molecules from the rough endoplasmic reticulum to late endosomes. It plays a role in immune defense. The Invariant Chain: An essential chaperone in antigen presentation The immune system functions through a finely tuned interplay of molecules … Read more >>