The absence of a costimulatory signal leads to clonal anergy

In this article, I briefly explain clonal anergy and its relation with a costimulatory signal. Clonal anergy A state of clonal anergy develops, when a na├»ve T cell engages its TCR with an antigen presented by an MHC, without a suitable costimulatory signal. It is a state, where the specific T cell clone shows no … Read more >>